Enhancement by Urine of Urinary Bladder Carcinogenesis1
نویسندگان
چکیده
The role of urine as a tumor-enhancing agent in urinary bladder carcinogenesis was investigated by using the heterotopically transplanted rat urinary bladder. Bladders removed from rats initiated with the carcinogen /V-butyl-/V-(4-hydroxybutyl)nitrosamine in drinking water for 4 or 10 weeks were heterotransplanted to syngeneic rats. Those heterotopically transplanted bladders receiving repeated instillations of normal rat urine subsequent to transplantation had a higher incidence of carcinoma than did those receiving 0.9% NaCI solution. These results suggest that normal urine may contain tumor promoter(s).
منابع مشابه
PHEOCHROMOCYTOMA OF THE URINARY BLADDER
One of the rarest tumors involving the urinary bladder is the pheochromocytoma. A case of pheochromocytoma of the urinary bladder in a young female suffering from headache and cystitis for many years is reported. Twenty-four hour urine VMA was normal. The patient was never hypertensive except during surgical manipulation of the tumor. Biopsy of the bladder resulted in massive hemorrhage.
متن کاملBacteriological study of urine and its relationship with histopathological findings of bladder and kidney in river buffalo (Bubalus bubalis)
BACKGROUND:Cystitis and pyelonephnitis in ruminants mostoften result from ascending urinary tract infection (UTI).OBJECTIVES: Investigating the prevalence of urine infection andits relationship with histopathological findings of bladder andkidney. METHODS: This study was carried out on 353 slaughteredbuffalos (143 female and 210 male) at Ahvaz abattoir, southwest ofIran. After slaughter, urinar...
متن کاملIs Foley Catheter Able to Drain the Bladder Completely in the Morning for Patients in ICU?
Introduction: Foley catheters are assumed to drain the bladder completely. It is known that uncompleted drainage leads to multiple complications, such as asymptomatic bacteriuria and urinary tract infection. Methods: From 116 patients, who were admitted to intensive care unit (ICU) for more than 24 hours, were enrolled in this study. To measure the urine level in bladder in the morning before a...
متن کاملTrichosomoides crassicauda Infection in Laboratory Rats with Histopathological Description in the Bladder Tissue
Introduction: Some postgraduate students reported the presence of a nematode infection, presumably, Trichosomoides crassicauda in the urinary bladder of rats (Rattus norvegicus) from the animal house of Tehran University of Medical Sciences (TUMS). We prompted to explore the prevalence of this infection among the rats of animal houses belonging to medical and veterinary research centers in Tehr...
متن کاملAnterior Urethral Valve and Diverticulum in a Neonate with Urinary Tract Infection
Introduction:Anterior urethral valve (AUV) is a rare congenital anomaly that can cause obstructive uropathy. AUV can lead to variable urinary tract symptoms, and if left untreated, it can result in end-stage renal disease. AUV should be immediately evaluated and managed. Herein, we present a neonate with AUV and diverticulum, who was treated by cystoscopy. Case report:A 11-day-old boy was ref...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
دوره شماره
صفحات -
تاریخ انتشار 2006